Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu"
Abstract
Department of Dermatovenerology, State University of Medicine and Pharmacy "Nicolae Testemitanu", Chișinău, Republic of Moldova, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltareIntroduction:
Cutaneous tuberculosis is a group of polymorphous and
varied manifestations of the skin and mucous membranes,
produced by infection with some species of Mycobacterium
tuberculosis complex. The specific primary lesion is the
lupoma, sometimes evolving into mutilating forms.
Purpose:
Lupus vulgaris particularities reported in two clinical cases.
Material and methods:
A 68-year-old female, presented for multiple infiltrative,
prominent erythematous plaques and placards with
various diameter, well contoured by a violaceus halo, with
irregular contour on the trunk. A 6-year-old boy presented
for brownish-red, soft papules with smooth surface on the
face and trunk. The lesions appeared 3 years ago; and 6
months ago after a minor trauma injury, the lesions have
spread.
Results:
Chest X-ray didn’t reveal any abnormalities. During
dermascopy the sign of “apple jelly” was found positive.
Histopathological exam found caseous necrosis,
tuberculoid granulomas composed of epithelioid cells and
Langhans giant cells, surrounded by mononuclear and a
dense lymphocyte infiltrate localized in the dermis.
Mantoux probe was 17 mm in diameter. Clinical
examination sustained by the histopathological exam and
Mantoux probe inferred the diagnosis of lupus vulgaris
(tuberculosis).
Conclusions:
The particularities of the presented cases with distinct
clinical signs, the histopathological presence of
granulomatous inflammation with specific cellular
appearance, the hyperergic Mantoux test and the lack of
characteristic pulmonary changes represent a casuistic
interest of lupus vulgaris
