Maternal-fetal infection of premature newborn

Abstract

Perinatal Center, Municipal Clinical Hospital no. 1, Chisinau, Republic of Moldova, Perinatology Laboratory, Mother and Child Institute, Chisinau, Republic of Moldova, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltareIntroduction. Maternal-fetal infection (MFI) occupies top places in morbidity and mortality in premature babies. Purpose. We determined the clinical-anamnestic peculiarities of MFI depending on its manifestation. Material and methods. A case-control study was conducted applying the clinical-anamnestic method, on a group of 133 children from mothers at risk of infection, of which 47 (35,33%) children with MFI (including 28 (59,57%) with localized infections (pneumonia) and 19 (40,42%) with sepsis) and 86 (64,66%) children without MFI (Figure 1). 59 children had a birth weight (BW). Results. 16 (84,21%) children with sepsis, compared to 5 (17,86%) children with pneumonia and 19 (22,09%) children without MFI were born in extremely severe condition (p<0,01). Conclusions. Neonatal sepsis is associated with extremely severe condition and is manifested mainly by cardiovascular and digestive disorders, as well as RDS