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Incidence and Early Course of Retlnonathy of Prematurity
Authors
Jan M. Botsford
Karen W. Braune
+31 more
George Cassady
Georgia A. Chrousos
John Clarkson
Byron H. Demorest
Frederick J. Elsas
Roberta Erickson
John T. Flynn
David S. Friendly
William S. Gilbert
Robert J. Hardy
Mohammad Jaafar
John A. Jones
Marshall P. Keys
James A. Kimble
Lanning Kline
Martin P. Kolsky
Patricia Ann Mercer
Donna O\u27Neill
John F. O\u27Neill
Earl A. Palmer
Edward S. Parelhoff
Ed Perraut
Dale L. Phelps
Cynthia L. Phillips
A. Raymond Pilkerton
David Plotsky
Alan M. Roth
David B. Schaffer
Betty Tung
Douglas Witherspoon
Malinda Young
Publication date
1 January 1991
Publisher
Health Sciences Research Commons
Abstract
In the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity (ROP), 4099 infants weighing less than 1251 g at birth underwent sequential ophthalmic examinations, beginning at age 4 to 6 weeks, to monitor the incidence and course of ROP. Overall, 65.8% of the infants developed ROP to some degree; 81.6% for infants of less than 1000 g birth weight. As expected, ROP incidence and severity were higher in lower birth weight and gestational age categories. Black infants appeared less susceptible to ROP, of all severity categories, than nonblack infants. The timing of retinal vascular events correlated more closely with postconceptional age than with postnatal age, implicating the level of maturity more than postnatal environmental influences in governing the timing of these vascular events. These results include the current incidence of various severity stages of ROP found in the United States and provide new. insight into the development of ROP. © 1991, American Academy of Ophthalmology, Inc. All rights reserved
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George Washington University: Health Sciences Research Commons (HSRC)
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Last time updated on 03/12/2020