Abstract
The architecture specifies how the system should be designed and built. Several architecture frameworks exist for implementing the architectural design process. However, shortcomings are identified in current architectural design processes, especially concerning volatile domains like healthcare. We claim that an iterative architectural design process is required, where the technical concerns are separated from the non-technical ones. Furthermore, a strong guiding vision is required. Based on our experiences from a biobank IT infrastructure process, we present a Continuous Renewability architectural design process that is modular, interoperable, controlled and abstracted, thus being capable of handling complex systems with severe uncertainties