ABSTRACT: This study utilizes unique data from the World Values Survey to test the hypothesis that fatalism and the practice of the Golden Rule influence the economic development of nations. We use standard econometric models that account for endogeneity to understand the relative roles of culture, productivity, institutions, and geography in explaining human flourishing. Our analysis supports Harrison’s cultural hypothesis and demonstrates that fatalism and altruism’s explanatory powers, in our full model, are no less powerful than productivity, institutions, and geography in explaining economic performance. However, transforming existing fatalistic and altruistic attitudes in a positive direction using public policy to provide greater support for human flourishing may prove more challenging than overcoming other development constraints