This paper discusses a prototype for a communication aid on a mobile phone to support a Deaf1 person visiting a public hospital pharmacy. The aim is to prevent problems of non-compliance to treatment due to poor communication between a Deaf patient and a pharmacist. We studied the communication exchange between pharmacists and Deaf patients in a pharmacy setting in order to extract the most relevant content exchange between the two parties. A prototype was developed on a mobile phone and iteratively tested using role plays, questionnaires and focus groups with pharmacy students and Deaf participants. The prototype allows pharmacists to input text and make selections that provide detailed medical instructions in signed language to a Deaf patient. The prototype demonstrates the feasibility of encoding a limited communication flow on a mobile device, with carefully sequenced sign language videos that a Deaf patient can watch and understand in order to take medicine correctly.Telkom, Cisco, Aria Technologies, THRIP, SANPADDepartment of HE and Training approved lis