Background: Among the bioactive metals, silver exhibits the highest toxicity to bacteria, viruses, and other eukaryotic microorganisms. A large number of bioactive Ag(I) coordination compounds with different ligand environment have been reported and, in particular, the derivatives containing weak Ag−O and/or Ag−N bonds can exhibit a high bioactivity, lower light stability, and inferior solubility in water than the compounds with rather strong Ag−S or Ag−P bonds. Herein we describe the synthesis and antimicrobial activity of two new silver(I) compounds that feature the {AgNO} or {AgSO} environments and were derived from semicarbazone and thiosemicarbazone type ligands.This study was supported by FCT and Portugal 2020 (projects PTDC/QUI-QIN/29697/2017, LISBOA-01 -0145-FEDER-029697, UID/QUI/00100/2013, and REM2013), and the RUDN University Program 5 -100. TAF acknowledges the FCT for BPD grant SFRH/BPD/119980/2016.info:eu-repo/semantics/publishedVersio
