Hoeing, Caitlin

Kelly, Kaitlyn

Perillo, Thomas

Wu, James K., MD

English

Lehigh Valley Health Network: LVHN Scholarly Works

Lehigh Valley Health Network LVHN Scholarly Works Research Scholars Poster Presentation Outcomes of Septal Myectomy on Patients with Hypertrophic Cardiomyopathy Caitlin Hoeing Kaitlyn Kelly Thomas Perillo James K. Wu MD Follow this and additional works at: https://scholarlyworks.lvhn.org/research-scholars-posters  Part of the Cardiology Commons This Poster is brought to you for free and open access by LVHN Scholarly Works. It has been accepted for inclusion in LVHN Scholarly Works by an authorized administrator. For more information, please contact LibraryServices@lvhn.org. Lehigh Valley Health Network, Allentown, PennsylvaniaPerioperative Risk Factor N %CHF 51 44.7Mitral Regurgitation 47 41.2LVOTO 46 40.4SAM 35 30.7AFib 24 21.1CAD 23 20.2Prior Pacemaker 18 15.8Dyspnea 12 10.5Postoperative Complication N %New Pacemaker 10 8.7Heart Block 8 7.0Kidney Failure 8 7.0New VSD Repair 5 4.4Extra Ventilator 3 2.6Excessive Bleeding 2 1.8BackgroundMethodsResultsConclusionsOutcomes of Septal Myectomy on Patients with Hypertrophic CardiomyopathyCaitlin Hoeing, Kaitlin Kelly, Thomas Perillo, James Wu, MDDivision of Cardiothoracic SurgeryFigure 2: Kaplan-Meier Curve of Septal Myectomy PatientsThe gradual drops in the curve illustrate promising survival rate for patients. The data suggests that this is statistically significant, p < 0.001.Classified• Single-center retrospective review of all septal myectomy patients from 2006-2020 at LVHNReviewed• Specific patient data gathered and assessed through in-house database• Data was recorded in a unique REDCap databaseAnalyzed• Descriptive statistics were used to analyze the significance of patient survival rates Objective• This study seeks to evaluate the survival rates of patients with HCM that underwent the septal myectomy procedure.Figure 1: Diagram of HCM and Septal Myectomy ProcedureFactorNumber of eventsa Number of censoredbSample sizeN % N %HCM Patients 14 12.28 100 87.72 114Table 1: Septal Myectomy Patient Mortality SummaryEvents = Death Censored = AliveTable 2: Pre-Septal Myectomy Risk Factors and Postoperative Complications• Hypertrophic Cardiomyopathy (HCM) is a condition in which a portion of the heart becomes thickened without an obvious cause• Hypertrophy = enlargement of tissue• Drug-resistant patients  Septal Myectomy• Surgical removal of enlarged portions of the heart• Previous studies have found promising outcomes that include low mortality rates and rare occurrences of major complications• Septal myectomy decreases symptoms of HCM• 114 total patients • 14 died (12.28%) • Average survival time of 1134.14 days (3.10 years)• 3 patients died within 30 days of the procedure (2.63%)• 2 died due to excessive bleeding• Major complications were not prevalent in the population• Data is statistically significant, p < 0.001• Survival rates are promising  only 12.28% died in a patient cohort that spans over 14 years• Patients with several comorbidities are at higher risk for the septal myectomy procedure• However, the overall survival rates are promising • Long-term survival rates of HCM patients that underwent septal myectomy illustrate success for this procedure• Future research is encouraged to evaluate long-term outcomes of septal myectomy over 20 years and understand the effects of pre-TAVR risk factorsReferences• Edwards, Anthony. “Transaortic Septal Myectomy: Techniques and Pitfalls.” Annals of Cardiothoracic Surgery, www.annalscts.com/article/view/15789/15860.• “Hypertrophic Cardiomyopathy.” MedlinePlus, U.S. National Library of Medicine, medlineplus.gov/ency/article/000192.htm.• Septal Myectomy, Johns Hopkins Medicine, www.hopkinsmedicine.org/health/treatment-tests-and-therapies/septal-myectomy.• “Septal Myectomy.” Cleveland Clinic, 6 May 2019, my.clevelandclinic.org/health/treatments/17461-septal-myectomy.

Outcomes of Septal Myectomy on Patients with Hypertrophic Cardiomyopathy

https://scholarlyworks.lvhn.org/cgi/viewcontent.cgi?article=1637&context=research-scholars-posters

Outcomes of Septal Myectomy on Patients with Hypertrophic Cardiomyopathy

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