[Excerpt] Central nervous system associated disorders are a leading cause of disability worldwide. In recent years targeted drug delivery nanoparticle based systems for intracellular application have been put forward has a possible therapeutic route to follow. In this sense the objective of the present report was to characterize and evaluate the possible applicability of recently developed carboxymethylchitosan/poly(amidoamine) (CMC/PAMAM) dendrimer nanoparticles in central nervous system (CNS) cell populations. Atomic force and transmission electron microscopy observations revealed that these nanoparticles possessed a nanosphere-like shape and sizes between 2–123 nm. [...]info:eu-repo/semantics/publishedVersio
