Fisher, Mathew

Pais, Célia

Mycoses

Universidade do Minho: RepositoriUM

Genotyping	fungal	outbreaks	and	molecular	epidemiology:	The	state	of	the	art	Célia	Pais1	&	Mathew	Fisher2	1Centro	de	Biologia	Molecular	e	Ambiental	(CBMA),	Departamento	de	Biologia,	Universidade	do	Minho,	Campus	de	Gualtar	4710-057	Braga	Portugal	2Imperial	College,	Department	of	Infectious	Disease	Epidemiology,	London,	England		The	processes	driving	infectious	disease	emergence	and	spread	are	reflected	in	their	 genetic	 diversity.	 Genotyping	 approaches	 are	 now	 an	 integral	 part	 of	research	in	infectious	disease	epidemiology.	Detailed	individual-	or	species-level	analyses	of	genetic	diversity	informs	our	understanding	of	disease	transmission	and	the	evolution	and	spread	of	antifungal	resistance.	Broader	genomic	analysis	of	 microbial	 communities	 within	 the	 host	 is	 revealing	 important	 interactions	between	 different	 fungal	 lineages,	 species	 and	 kingdoms,	 their	 response	 to	interventions	and	 their	 role	 in	 shaping	 the	 immune	 response	 to	 infection.	This	'meet	 the	 expert'	 session	 will	 consider	 the	 scientific	 potential	 for	 high-throughput	 genotyping	 data	 in	 fungal	 disease	 epidemiology	 and	 the	 new	opportunities	 offered	 by	 advances	 in	 genetic	 sequencing	 technology.	 We	 will	consider	 the	 advantages	 and	 disadvantages	 of	 currently	 used	 genotyping	techniques,	 the	 types	of	 analyses	 that	each	platform	supports,	 and	 the	 rapidly-developing	opportunities	that	are	afforded	by	new	genotyping	technologies.	Our	examples	will	be	chosen	to	illustrate	the	spectrum	of	infectious	fungi	that	impact	humans	and	other	animals.	

Genotyping fungal outbreaks and molecular epidemiology: the state of the art

http://repositorium.sdum.uminho.pt/bitstream/1822/50364/1/Meet%20the%20expert%20session.pdf

Genotyping fungal outbreaks and molecular epidemiology: the state of the art

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Universidade do Minho: RepositoriUM

Universidade do Minho: RepositoriUM