Whether the complex and time-intensive requirements for administering PRP warrants its use for intra-articular (IA) therapy in OA is in question and should be examined. If PRP is at least or even more effective than corticosteroids or hyaluronic acid (HA) for relieving pain and restoring function, then it can be recommended with confidence to OA patients who are appropriate candidates for intra-articular injections. In addition, if its beneficial effects are more durable than other IA agents, it may become the preferred treatment of choice
