Vitamin D is a cholesterol derived, fat soluble, steroid substance present in the body. It plays an
important role in the female reproductive system and regulating its functions. It is believed that
vitamin D improves the endometrial thickness. The relationship between the level of vitamin D and
fertilization, embryo quality and Intracytoplasmic sperm injection outcome remains controversial till
now.
The aim of the study to assess the relation of vitamin D levels in serum and follicular fluid with
Intracytoplasmic sperm injection outcome.
Eighty-eight women were enrolled in this study. They were classified according to the cause of
infertility into case group with female factor and control group with male factor. All women were
undergoing Intracytoplasmic sperm injection procedure. Serum and follicular fluid vitamin D levels
were measured on the day of oocyte retrieval.
It was found that no significant differences in either serum or follicular fluid level of vitamin D
between the case and control groups and higher serum and follicular fluid levels of vitamin D are
associated with better pregnancy rates after Intracytoplasmic sperm injection. Further studies on
vitamin D in male are required to prove its role in the Intracytoplasmic sperm injection.
The present study concluded that no significant differences in either serum or follicular fluid level
of vitamin D between the case and control groups and higher serum and follicular fluid levels of
vitamin D are associated with better pregnancy rates after Intracytoplasmic sperm injection
