Laccase (EC 1.10.3.2) is a multicopper oxidase which reduces oxygen to water and simultaneously performs one-electron oxidation of many aromatic substrates [7]. Laccases catalyze the removal of a hydrogen atom from the hydroxyl group of methoxy-substituted monophenols , ortho- and para-diphenols, but it be able also to oxidize other substrates such aromatic amines, syringaldazine, and non-phenolic compounds to form free radicals [8]