The interest in Kluyveromyces lactis (K. lactis) has begun in academia due to its ability to metabolize the betaglycoside
(1). Since then, this yeast has been considered a model organism for studies in genetics and physiology (2).
This yeast had its genome sequenced back in 2004 (3) and recently we have published a full metabolic re-annotation
of its genome (4). This re-annotation can be used, among other applications, to reconstruct genome-scale metabolic
models.
These models allow anticipating a given organism's phenotype from its genome sequence. The reconstruction of
biochemical networks is, currently, a valid alternative to microorganisms modelling as the output provided by the in
silico simulations permits focusing on experiments with promising results.
Thus, we propose a new fully compartmentalised genome-scale metabolic model for K. lactis, the iOD1759 which
comprises 1759 metabolic genes