In the last two decades the advances in rapid prototyping and tooling (RPT) technologies made possible the use of materials alternative to steel in some mould components. They also have allowed novel fabrication strategies and new ways of thinking on the production of injection moulds for short series of plas-tics parts. These technologies induced a new generation of toolmaking techniques. In the scope of the devel-opment project Hybridmould 21 the pros and cons of some RPT technologies were studied to fabricate moulding blocks and inserts for hybrid injection moulds for large plastics parts. Essentially, the studies aimed at finding the best solution for quick production and compliance with specific product requirements, such as complex features, complex cooling layout and large size (around 1 m2) in short production series. This paper discusses the main advantages and disadvantages associated to a number of different RPT technologies for the manufacture of moulding element.Program QREN - ‘Concessão de Incentivos Financeiros no âmbito do Sistema de Incentivos à Investigação e Desenvolvimento Tecnológico’ (contract 2010/013307) – Project Hybridmould 2