In this paper we review recent advances on the practice and theory of process control with
particular emphasis to the operation of bioreactors. We present in detail a case-study on the
modelling, model-based identification and adaptive control of fed-batch baker's yeast
fermentation.Junta Nacional de Investigação Científica e Tecnológica (JNICT) - contract numbers BD/224/90-IF, BD/1476/91-RM.Instituto Nacional de Investigação Científica (INIC)