Centers of coordination (CCs) are specific points where the mechanical forces converge in epimysial fascia to coordinate the movement of a joint in a specific plane of motion. It is known that the loose connective tissue between layers of fascia are rich in hyaluronan (HA), allowing normal gliding of the fascial layers. Densifications in the fascia are described as areas of increased concentration of HA molecules, causing a polymerization of the HA chains. This entanglement of the HA chains causes a change in the consistency of the HA4, causing a restriction in the fascial gliding, leading to dysfunction and pain. Although previous studies used un-embalmed cadavers to study fascia, this study attempts to identify and examine the HA content in CCs and non-CCs using embalmed cadaver tissue
