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Evaluation of Nanosphere Verigene RT-PCR and Microarray Assay Versus Culture in the Detection of Enteric Pathogens

Abstract

With gastroenteritis as the second leading cause of morbidity and mortality worldwide (Guerrant et al. 2001), it is imperative to have a laboratory method which is highly rapid, sensitive, and cost-effective to aid in the diagnosis and treatment of affected patients. This validation study seeks to evaluate the Nanosphere Verigene real-time PCR and microarray assay as a potential replacement for the current culture-based methods of testing stool samples for enteric pathogens in the Bridgeport Hospital microbiology lab

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