Kanunik, T. S.

Riabokon, Ye. N.

Tokar, A. A.

Volkova, O. S.

Electronic Archive of the Ukrainian Medical Stomatological Academy

aesthetic appearance. Percussion of teeth, reaction to cold was painless. In the comparison group at 6 
and 12 months, a high strength of the material and an anticaries effect were also observed [4].
Conclusion: Thus, the conducted study showed that the use of the material "Ketac 
Molar Easymix" (ЗМ, ESPE) in childhood is not expensive and due to its properties has good long­
term results, it is recommended for wide clinical practice. The use of "Ketac Molar Easymix" (ЗМ, 
ESPE) glass-ionomer for sealing temporary and permanent teeth in children can significantly reduce 
the cost of treatment while maintaining the quality of the seals at the level of the best imported 
analogues, which is especially important in modern socio-economic conditions.
Reference
1. Reis Lda S., Chinelatti M.A., Corona S.A. et al., Palma-Dibb R.G., Borsatto M.C. Influence of air 
abrasion preparation on microleakage in glass ionomer cement restorations // J. Mater. Sci. Mater. 
Med. 2004. - Vol.15, № 11. -P.1213-1216.
2. Yip H.K., Smales R.J., Yu C. et al. Comparison of atraumatic restorative treatment and 
conventional cavity preparations for glass-ionomer restorations in primary molars: one-year results // 
Quintessence Int. 2002. - Vol.33, № 1. - P.17-21.
3. Donly K.J., Henson T. Glass ionomer cement restorations for contemporary pediatric dentistry // 
Alpha Omegan. 2005. - 98, № 4. - P.21-25.
4. Lohbauer Ulrich. Dental Glass Ionomer Cements as Permanent Filling Materials? Properties, 
Limitations and Future Trends/ Lohbauer Ulrich // Materials. 2010. -N 3. -P. 76-96.
ANALYSIS OF TH E EFFECTIVENESS OF IM M UNOM ODULATING ANTISEPTICS 
"M IRA M ISTIN " IN COM PLEX TREATM ENT OF PERIODONTAL DISEASES
RIABOKON YEN., TOKAR A.A., VOLKOVA O.S., KANUNIK T.S.
Kharkov National Medical University, Kharkov, Ukraine
Relevance: Currently, it has been proven that the microbial factor plays an important role in 
the development of periodontal diseases. It is obvious that the mechanical removal of plaque is not 
enough to control its re-deposition and the manifestation of pathogenic properties. It is necessary to 
direct the formation of plaque with the maintenance of normal microbial composition by stimulating 
the natural protective systems of the oral cavity and suppressing the vital activity of pathogenic 
bacteria with the help of drugs [1,2].
Among the means of antimicrobial action used in dental practice, includes a broad spectrum 
antiseptic "Miramistin" ("Darnitsa", Ukraine).
Objective: To analyze the effectiveness of the use of immunomodulatory antiseptic 
"Miramistin" ("Darnitsa", Ukraine) in the complex treatment of periodontal disease.
M aterials and methods: From among those who applied for dental care at the USC KNMU, 
31 people were selected, the average age was 41.8 (18 women, 13 men) with a diagnosis of chronic 
generalized periodontitis (CGP) primary, 1, 2 severity degree without concomitant pathology. The 
diagnosis of CGP was established according to the classification of periodontal tissue diseases 
(Danilevsky, 1994). Treatment of HP was performed according to an individual plan, in which all 
patients included rational oral hygiene, antiseptic treatment of periodontal tissues, removal of 
mineralized and non-mineralized dental deposits, elimination of local irritants and premature 
contacts. According to indications, depulping of teeth, closed curettage of periodontal pockets, 
removal of defective teeth, selective grinding and splinting of mobile teeth and finger massage were 
performed [5].
77
The treatment plan of the patient was made individually depending on the severity of 
periodontitis. For the local anti-inflammatory therapy, the drug Miramistin (“Darnitsa”, Ukraine) was 
used.
In order to relieve inflammatory manifestations in periodontal tissues, achieve 
immunomodulating and membrane-stabilizing effect, improve reparative regeneration and gum 
barrier function, increase the effectiveness of treatment, increase periods of remission, as well as 
avoid additional allergization, 0,5% ointment Miramistin was used in all patients ("Darnitsa", 
Ukraine) [3, 4]. Miramistin was applied to the near-toothed tissues under individual caps. 
Manipulations were performed daily. The number of sessions depended on the severity and 
effectiveness of the treatment of CGP and ranged from 7 to 13 procedures.
Results: The evaluation of the effectiveness of the treatment was carried out after 1 and 3 
months. Patient complaints were absent in 65% of cases. It was noted the absence of pain in the gums 
in 70%. Gingival bleeding was absent in 30% of patients. Indicators GI, PMA, SBI were lower than 
the primary survey in 65%. In other cases, the gum is pale pink in color, tight to the dental tissues.
Conclusions: The conducted clinical studies have shown that complex treatment of chronic 
generalized periodontitis with the use of immunomodulating antiseptic “Miramistin” (“Darnitsa”, 
Ukraine) provides more stable remission and prolongs its terms.
Reference
1. Сидельникова Л.Ф. Рання дiагностика захворювань пародонту в молоді - основа 
профілактики та превентивного лікування генералізованного пародонтиту 
(Л.Ф. Сидельникова, М.Ю. Антоненко, Дімітрова Г.Г.(Ткаченко). Науковий вісник 
Національного медичного університету ім. Богомольця. 2010. №4 (31). С. 99-102.
2. Димитрова (Ткаченко) А.Г. Контролируемая индивидуальная гигиена полости рта - важный 
этап противовоспалительной терапии генерализованного пародонтита у лиц молодого 
возраста. Современная стоматология. 2015. №1.
С. 23-26.
3. Яров Ю.Ю., Мельник В.В. Состояние местного иммунитета полости рта у больных с 
разными уровнями гигиены полости рта. Український стоматологічний альманах. 2013. №4. 
С. 25-28.
4. Кулаков А.А., Зорина О.А., Борискина О.А. Роль защитных факторов организма в 
потогинезе воспалительных заболеваний пародонта. Стоматология. 2010. № 6. С. 73-77.
5. Авдєєв О.В. Лікування дистрофічно-запальних захворювань пародонта при різній 
реактивності організму. Вісник стоматології. 2012. №3. С. 33-37.
ДО ПИТАННЯ ДІАГНОСТИКИ УСКЛАДНЕНЬ 
Х РО Н ІЧН О ГО  ГРАН У ЛЮ Ю ЧО ГО  ПЕРІОДОНТИТУ
САЛЮК ОД.
Державний заклад «Дніпропетровська медична академія МОЗ України»,
м. Дніпро, Україна
Одним з ускладнень хронічного гранулюючого періодонтиту є підшкірна гранульома. 
Вона виникає при розповсюдженні хронічного гранулюючого осередку під окістя та в м’які 
тканини, що оточують щелепи -  під слизову оболонку і підшкірну клітковину. Хоча більш 
звичним для лікаря-стоматолога при діагностиці хронічного гранулюючого періодонтиту є 
розміщення устя нориці на яснах в ділянці проекції верхівки причинного зубу.
78


Analysis of the effectiveness of immunomodulating antiseptics "Miramistin" in complex treatment of periodontal diseases

http://elib.umsa.edu.ua/jspui/bitstream/umsa/13542/1/Analysis_of_the_effectiveness.pdf

Analysis of the effectiveness of immunomodulating antiseptics "Miramistin" in complex treatment of periodontal diseases

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