'Royal College of Obstetricians & Gynaecologists (RCOG)'
Abstract
A one-pot three-step sequence involving Rh-catalyzed alkene hydroacylation, sulfide elimination and Rh-catalyzed aryl boronic acid conjugate addition, delivers products of traceless chelation-controlled hydroacylation employing alkyl aldehydes. The stereodefined β-aryl ketones are obtained in good yields with excellent control of enantioselectivity. Good variation of all three reaction components is possible
