10.1186/1477-7819-9-12World Journal of Surgical Oncology9

A Gronchi

Association of Directors of Anatomic and Surgical Pathology

AT Deyrup

Brian Kim Poh Goh

C Fletcher

CP Raut

D Shibata

DC Linehan

DM Thomas

DP Jaques

FC Eilber

G Lahat

I Ardoino

JJ Lewis

JS Liles

JW Kilkenny

Khee Chee Soo

London LPJ Ooi

M Trojani

Melissa Ching Ching Teo

Min Hoe Chew

MKB Parmar

MT Ballo

MW Kattan

OJ McCallum

PC McGrath

PHA Nijhuis

Pierce Kah Hoe Chow

PW Pisters

RL Jones

RM Mayberry

S Bonvalot

S Singer

Ser Yee Lee

SJ Neuhaus

ST Wong

TM Pawlik

Wai Keong Wong

WM Mendenhall

Ser Lee

Brian Goh

Melissa Teo

Min Chew

Pierce Chow

Wai Wong

Khee Soo

Springer - Publisher Connector

Retroperitoneal liposarcomas: the experience of a tertiary Asian center

Abstract Background Liposarcoma is the single most common soft tissue sarcoma in the retroperitoneum. Materials and methods A retrospective review of patients with primary retroperitoneal liposarcoma treated between June 1990 and June 2005 were conducted to evaluate the clinical results of resection for retroperitoneal liposarcomas (RPLS) and the prognostic factors for disease recurrence and patient survival in an Asian population. Results Twenty-one patients operated on for curative intent (12 Males, 9 Females; mean age: 52.4 years) were evaluated. Of these, 13 presented with tumors that were well differentiated (61.9%), 4 (19.0%) with myxoid/round cell, 3 (14.3%) with dedifferentiated and 1(4.8%) with pleomorphic morphology. The median tumor burden was 36 cm (9-83). Median follow-up time was 62 months. There was no peri-operative mortality and morbidity occurred in 6(28.6%) patients. Surgical margins were involved in 10(47.6%) patients. Resection of contiguous organs was required in 15(71.4%) to achieve gross surgical margins. Eleven out of the 21(52%) of the patients had recurrence of the tumor. Median disease-free survival was 19 months and the overall 3- and 5-year survival rate was 87% and 49% respectively. Conclusion An aggressive surgical approach in both primary and recurrent RPLS in our institution is associated with 3- and 5-year survival rate of 87% and 49% respectively. Contiguous organ resection is often required to achieve local control.</p

Chow Pierce

Chew Min

Teo Melissa

Goh Brian

Lee Ser

Wong Wai

Ooi London LPJ

Soo Khee

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World Journal of Surgical Oncology

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Retroperitoneal liposarcomas: The experience of a tertiary Asian center

Retroperitoneal liposarcomas: The experience of a tertiary Asian center

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Springer - Publisher Connector

Springer - Publisher Connector

Directory of Open Access Journals

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