This research uses a net present value model developed on Microsoft Excel to determine the feasibility and advisability of a lignocellulosic ethanol supply chain in Calvin, Oklahoma. The research addresses challenges facing Oklahoma with switchgrass production. Dedicated energy crops (DEC) such as switchgrass, can be produced on marginal or Conservation Reserve Program (CRP) land. DECs provide an avenue for biomass to be produced while not hindering or competing with conventional crop production or rangeland uses. Considering the advantages of switchgrass biomass production, it is important to establish a successfully optimized lignocellulosic supply chain. Supply chain for feedstock delivery can be difficult to manage and optimize based on the infrastructure, feedstock availability, farm field locations, and length of haul. These factors play a key role in determining the feasibility and are heavily considered for this research due to the limitations faced by Oklahoma's infrastructure and feedstock availability. Transportation cost implications are of most importance when considering a cellulosic ethanol supply chain. For this research, transportation costs were quantified to reflect issues faced within Oklahoma. In conclusion, for the average yield state of 1.5 tons acre-1, a 69 million gallon capacity (50 million gallons production capacity) biorefinery there will be a required 81,707 truckloads per year. In addition, in the average yield state of nature, under no given price are the projects feasible. Compared to states with a busting corn market with higher yields, multiple inputs, and improved rural infrastructure, Oklahoma has to pay a high premium for the delivery of feedstock. Into the future, Oklahoma will have to improve rural infrastructure and improve yields acre to become profitable