Dietary histone deacetylase inhibitors in chemoprevention

Abstract

Cancer has remained the second leading cause of death in the United States, with the gap between that and the number one cause, heart disease, decreasing significantly over the past 50 years. As the prevalence of cancer increases throughout the United States, research continues to analyze new aspects of its prevention and treatment (Heron & Anderson, 2016). Within the field of nutrition, it has become increasingly apparent the importance of preventative medicine through dietary components. A recent area of interest within the field of nutrition and epigenetics is the use of histone deacetylase (HDAC) inhibitors as chemopreventative agents

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