Synthetic prions

Abstract

Neuropathology of human prion diseases -- The nature of the infectious agents : prp models of resistant species to prion diseases (dog, rabbit and horses) -- Inducing transmissible prion diseases with recombinant fibrils : a new concept on genesis and evolution of infectious prions -- Synthetic prions -- Recent developments in cell biology : role of glycosylation in prion diseases -- Transmissibility of prion diseases in rodent models : atypical strains -- Pre-mortem diagnostic screening for transmissible spongiform encephalopathies by proteomic approaches -- Added value of biochemical tools for the diagnosis of human prion disease -- Anti-prion strategies for in vivo gene therapy assays

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