Mild cross-coupling reaction between benzylboronic esters with carbonyl compounds and some imines was achieved under visible-light-induced iridium-catalyzed photoredox conditions. Functional group tolerance was demonstrated by 51 examples, including 13 heterocyclic compounds. Gram-scale reaction was realized through the use of computer-controlled continuous flow photoreactors.Uniqsis Ltd and Mark Ladlow for the generous loan 236
of a Photosyn reactor. Y.C. thanks Pfizer for funding the 237
postdoctoral fellowship. The authors also gratefully acknowl- 238
edge financial support from H2020-FETOPEN-2016-2017 239
program of European commission (S.V.L.; grant agreement 240
no.: 737266-ONE FLOW)
