Development of lactobacilli therapy to prevent recurrent urinary tract infections in females

Abstract

Culture-dependent PCR-amplified rRNA gene restriction analysis and culture-independent (PCR-denaturing gradient gel electrophoresis) methodologies were used to examine vaginal lactobacilli from Brazilian women who were healthy or had been diagnosed with vulvovaginal candidiasis (VVC) or bacterial vaginosis. Only Lactobacillus crispatus was detected accordingly by both methods, and H O -producing lactobacilli were not associated with protection against VVC. Copyright © 2008, American Society for Microbiology. All Rights Reserved. 2