Bameri, Delaram

Shahshahani, Masih

English

Simorgh Research Repository

 أ                              ب   دانشگاه علوم پزشكي كرمان                                             دانشكده دندانپزشكي هاي دهان و دندان مركز تحقيقات بيماري ثر بر سلامت دهان و دندانؤهاي اجتماعي ممركز مولفه  :هنامپايان  دندانپزشكي  جهت دريافت درجه دكتراي                                      :عنوان بخش پاتولوژي دانشكده  هاي ارجاع داده شده بههاي سر و گردن در بيوپسيبدخيمي فراوانيبررسي  8931تا  8831هاي شهيد باهنر وشفا از سال و بيمارستان دندانپزشكي  : راهنما ستادا  كلانتريمهسا دكتر   استاد مشاور: دكتر سارا امان پور   :پژوهش و نگارش                                                 دلارام بامري                                                        سيد مسيح شهشهاني                                                          5711 :شماره پايان نامه                                                           8931-99سال تحصيلي:   ج   Kerman University of Medical Sciences Dental School A Thesis Submitted in Partial Fulfilment of the Requirement for the  Specialist Degree in Surgery Dentistry  Title: Evaluation of the Frequency of Malignant Tumors of Head and Neck in the Pathology Departments of Kerman Dental School, Shafa and Bahonar Hospitals Between the Years 2009-2019.  Supervisor Dr. Mahsa Kalantari  Advisor Dr. Sara Aman pour   Submitted by Delaram Bameri Seyed Masih Shahshahany     Year 2020                                                                                 Thesis No: 1175  د  چکيده:داشتن اگاهي از فراواني د.باشنجهان ميين سرطان شايع در سرتاسر هاي سر و گردن ششمسرطان مقدمه:تومورهاي  فراوانيهدف از اين مطالعه بررسي  اين ضايعات براي برنامه ريزي هاي سلامت الزامي ميباشد.هاي پاتولوژي دانشكده دندانپزشكي كرمان و ساله در بخش 11طول يک دوره بدخيم سر و گردن در  هاي شفا و باهنر بود.بيمارستانبدخيم ناحيه سر  هاي پاتولوژي تمامي موارد با تومورهايدر اين مطالعه گذشته نگر، گزارش روش کار:جنسيت و سن  دموگرافيک شاملمورد بررسي قرار گرفت. اطلاعات  8931تا  8831 و گردن از سال  SSPSها با نرم افزار آماري هيستوپاتولوژي جمع آوري شد. دادهبيماران، محل ضايعات و تشخيص تجزيه و تحليل شدند  rehsiFو  AVONA،  erauqs ihCهايبا استفاده از آزمون 02سخه ن .)50.0<P( ٪66/9. %) تومور هاي بدخيم ناحيه سر و گردن بودند  3/5عدد ( 3002 ،ضايعه 56175از تعداد  :يافته هاترين سال بود. حنجره شايع 25/18 ±51/59در زمان تشخيص  سنيزن بودند. ميانگين  ٪33/1موارد مرد و قرار  %)  51%) و تيروئيد ( 71/3%) بود و پس از آن به ترتيب لب و حفره دهان ( 64/2محل درگيري ( 0/50داشتند. بيماران با تشخيص كارسينوما نسبت به بيماران مبتلا به ساركوما و لنفوما سن بالاتري داشتند () بود و به دنبال آن به ترتيب پاپيلاري % 46/5ترين تشخيص (). كارسينوم سلول سنگفرشي شايعP> %) قرار داشتند. 01/1%) و لنفوما ( 31/9(ي تيروئيد كارسينوماهاي ساير مناطق ايران ر و گردن در اين مطالعه با يافتهشيوع بالاتر سرطان حنجره در ناحيه س :نتيجه گيریهاي جغرافيايي تواند ناشي از تفاوتهاي سر و گردن ميسرطانها در الگوهاي ساير مطابقت دارد. تفاوت و همچنين عوامل خطر و سبک زندگي متفاوت در سراسر جهان باشد. .نئوپلاسم سر و گردن، سرطان،: کلمات کليدی   ه  Abstract Introduction: Head and neck cancers are the sixth common cancer worldwide. It is necessary to inform the frequency of these lesions for health planning.  The aim of this study was to investigate the frequency of malignant tumors of head and neck over a period of 11 years in the Pathology Departments of Kerman Dental School, and Shafa and Bahonar hospitals. Methods: In this retrospective study, pathology reports of all cases with malignant tumors of head and neck region from 2009 to 2019 were reviewed. Demographic data, including sex and age, location of the lesion and histopathological diagnoses were recorded. Data were analyzed with SPSS statistical software (V.20) using the chi-square, ANOVA and Fisher exact tests (p-value <0.05).  Result: Out of total 57165 lesions, 2003(3/5%) were malignant tumors of head and neck region. 66.9% were male and 33.1% were female. The mean age at the time of diagnosis was 52.81±15.95 years. Larynx was the most common affected site (46.2%), followed by lip and oral cavity (17.3%) and thyroid (15%). Patients with a diagnosis of carcinoma were older than those with sarcoma and lymphoma (p<0.05). Squamous cell carcinoma was the most common diagnoses (64.5%), followed by papillary thyroid carcinoma (13.9%) and lymphoma (10.1%), respectively. Conclusion: The higher incidence of laryngeal cancer in the head and neck region in this study is in agreement with findings of the other parts of Iran. The differences in the patterns of other head and neck cancers could be due to geographical differences and also different risk factors and lifestyles all over the world. Keywords: Head and neck, Cancer, Neoplasm.     و  فهرست مطالب ب عنوان ز فهرست جداول ح فهرست نمودارها ط چكيده فارسي ي چكيده انگليسي 1 فصل اول كليات تحقيق 2 بيان مسئله -1-1 4 اهداف: 4 هدف اصلي -1-2-1 4 اهداف فرعي -1-2-2 4 هدف كاربردي -1-2-3 5 سوالات و فرضيات پژوهش -1-2-4 6 فصل دوم مروري بر كتب و مقالات 7 مقدمه -2-1 41 مروري بر مقالات -2-2 91 فصل سوم روش تحقيق 02 نحوه اجرا -3-1 22 هاي پژوهشابزار جمع آوري داده -3-2 22 هاو تجزيه و تحليل دادهروش محاسبه حجم نمونه  - 3-3 32 اخلاقيملاحظات  -3-4 42 هافصل چهارم يافته 73 فصل پنجم بحث و نتيجه گيري 83. بحث 44 محدوديت ها و پيشنهادات 54 نتيجه گيري 64 منابع     ز   فهرست جداول صفحه عنوان                                                      12 سر و گردن هاي ناحيهبراي بدخيمي  DCI: طبقه بندي 3-1جدول گروه اصلي بر حسب جنس، ميانگين سني و  3توزيع فراواني ضايعات در : 4-1جدول  محل شايع درگيري 62ترين نوع بدخيمي ضايعات بر حسب مكان سني و شايع توزيع جنسي، :4-2جدول  درگيري 82 03 سنيترين نوع بدخيمي ضايعات بر حسب دهه توزيع مكاني، جنسي و شايع: 4-3جدول هاي هيستوپاتولوژيک توزيع فراواني ضايعات شايع در هر يک از زيرگروه: 4-4جدول  بر حسب جنس و سن 13               ح  فهرست نمودارها صفحه عنوان                   33  ضايعه شايع در بررسي هيستوپاتولوژي 01: توزيع فراواني  4-1نمودار  43 ضايعه شايع در بررسي هيستوپاتولوژي در مردان 01فراواني توزيع : 4-2نمودار  43 ضايعه شايع در بررسي هيستوپاتولوژي در مردان 01توزيع فراواني  :4-3نمودار فراواني ضايعات بر حسب تشخيص هيستوپاتولوژيک در هر سال توزيع : 4-4نمودار  )8831-8931( 53 )8831 – 8931در هر سال  ( بر حسب جنسيتفراواني ضايعات توزيع : 4-5نمودار    63           ط  :عبانم  1- Massa ST, Osazuwa-Peters N, Christopher KM, Arnold LD, Schootman M, Walker RJ, et al. 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بررسی فراوانی بدخیمی های سر و گردن در بیوپسی های ارجاع داده شده به بخش پاتولوژی دانشکده دندانپزشکی و بیمارستان¬های شهید باهنر وشفا از سال ۱۳۸۸ تا ۱۳۹۸

http://eprints.kmu.ac.ir/34952/1/7845.pdf

بررسی فراوانی بدخیمی های سر و گردن در بیوپسی های ارجاع داده شده به بخش پاتولوژی دانشکده دندانپزشکی و بیمارستان¬های شهید باهنر وشفا از سال ۱۳۸۸ تا ۱۳۹۸

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