This thesis is a commentary and exegesis on François Laruelle’s 1977 text Nietzsche contre Heidegger with a focus on the concept of the ‘Nietzschean problematic.’ It explores Laruelle’s use of Nietzsche by comparing his reading with that of Gilles Deleuze. This relation is explored in Deleuze and Laruelle’s reading of the Nietzschean problematic through the distinction between complementarity and supplementarity to enable a reading of Laruelle’s text as an extension of Deleuze’s project. This extension is one that simultaneously overturns what it extends. Laruelle’s aim is presented as a ‘machinic materialism’ infused with Derridean différance. Over the course of the thesis many of Laruelle’s concepts from Nietzsche contre Heidegger—machinic and political materialism, politico-libidinal cut, chiasm, quadripartite—are explored to provide a more concise picture of the Nietzschean problematic and what this problematic can do