Traditional point-of-care malaria diagnostic platforms lack sensitivity, the devices of them are bulky and expensive. To meet the demand for malaria diagnosis in malaria-endemic countries with low-resource, a cost-effective, easy-to-use, high-sensitivity and rapid diagnostic platform is needed. Here, we report the tunnel magnetoresistance (TMR) sensor to diagnose malaria by detecting the hemozoin. The hand-held device of TMR diagnostic platform consists of a cylindrical magnet, a TMR sensor, an Analog-Front-End circuit, and a microprocessor to display the results. The test result shows that this device can detect the synthetic hemozoin in labs and have the potential to be a point-of-care diagnosis
