Department of Oncology Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova, The 8th International Medical Congress for Students and Young Doctors, September 24-26, 2020Introduction. Endometriosis is a benign gynecological estrogen-dependent disease
characterized by endometrium-like tissue outside the uterus. The disease affects approx. 6-10%
of women of reproductive age. The benign endometrial tumor also known as ’’chocolate cyst”
affects 17-44% of women with endometriosis. Etiological theories explaining the endometrial
lesions are: reflux of endometrial tissue via fallopian tubes during menstruation, coelomic
metaplasia, vestiges of embryonic cells and lymphatic and vascular proliferation. The golden
standard in diagnosis of endometrial tumors is laparoscopy. Transvaginal ultrasound does not
help in initial diagnosis, but nonetheless can help in telling apart the endometrial from other
benign ovarian tumors, while MRI helps in differentiating endometrial ovarian tumors from
other ovarian cysts.
Aim of the study. Evaluation of risk factors and methods of diagnosis of endometrial ovarian
tumors. Materials and methods.. Lot of patients: 27 patients with endometrial ovarian tumors who
were hospitalized and received treatment at PMSI OI of the Republic of Moldova between
2014 and 2019.
Results. Total number of patients enrolled in the study: 27 patients, 25-45 years (age of highest
incidence) - 15 patients (55,5%). The most frequent symptoms: pelvic pain - 27 patients
(100%), dysmenorrhea - 9 patients (33,3%), dyspareunia- 5 patients (18,51%), metrorrhagia -
3 patients (11,1%).Bimanual examination of 12 patients (44,4%), revealed a smooth, elastic
mass. According to laboratory data, 19 patients (70,37%) showed high CA 125 values, and 14
patients (51,8%) high estradiol values. Diagnostic imaging: ultrasound - 27 patients (100%),
CT -7 patients (25,92%), MRI - 3 patients (11,1%). Laparoscopic methods: diagnostic
laparoscopy - 12 patients (44,4%). All patients have received surgical treatment: surgery under
laparoscopy - 12 patients (44,4%), laparotomy - 15 patients (55,5%).
Conclusions. 1.Age and high estrogen levels are among the main factors which lead to
endometrial ovarian tumors. 2.Pelvic pain is the main symptom shown by patients followed
by dysmenorrhea, dyspareunia, and metrorrhagia. 3.Laparoscopy is the golden standard in the
diagnosis of endometrial ovarian tumors