Dodani, S

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eCommons@AKUDepartment of Family Medicine Medical College, PakistanAugust 1998Evaluation of chest pain in general practiceS DodaniAga Khan UniversityFollow this and additional works at: https://ecommons.aku.edu/pakistan_fhs_mc_fam_medPart of the Family Medicine CommonsRecommended CitationDodani, S. (1998). Evaluation of chest pain in general practice. Journal of Pakistan Medical Association, 48(8), 254-256.Available at: https://ecommons.aku.edu/pakistan_fhs_mc_fam_med/211Evaluation of Chest Pain in General PracticePages with reference to book, From 254 To 258 Sunita Dodani ( Department of Family Medicine, Aga Khan University Hospital, Karachi. ) Chest pain can be one of the most challenging and difficult presentations with which a doctor is faced.Concerns about serious heart and lung disease intermix with more common problems like depression,anxiety, esophageal dysfunction and musculo- skeletal disease.Although most chest pains prove to be harmless, the primaiy physician must be skilled in quickly andaccurately recognizing the patient with serious underlying cardiovascular or pulmonary pathology.In the office setting, the evaluation is predominantly clinical, based on data available from the histoiyand physical examination. ECG and perhaps a Chest X-ray may be available. Of particular challenge isthe assessment of the patient with atypical chest pain.Most structures within and about the thorax are capable of producing chest pain, as is psychopatholoy.The differential diagnosis of chest pain can be organized along anatomic lines1 (Table).Work-upFaced with a patient complaining of chest pain, there is the temptation to proceed directly to ‘theplethora of sophisticated diagnostic studies for detection of comnaiy artery disease. However, the costand the false-positve rate of suchpiernatwe testing are likely to be unacceptably high because of the lowpretest probability of CHD in unselected patients2.More useful is a work-up strategy that attempts to determine and stratify CHD risk on the basis of aninitial histoiy, physical examination and ECO.HistoryEstimating probability of coronary diseaseA careful chest pain description is critical. The prevalence of angiographically confirmed CHDapproaches 90 percent in persons with a classic story for angina.In the Framingham study2, patients presenting with new onset of definite angina had relative risk of acoronary event over 2 years of 3.0 for men and 5.0 for women. Relative risk fell for those with possibleangrnato 3.0 for men and 2.9 forwomenandto 1.3 for men and 0.8 for women with non-angjnal chestpainAssessment of history for other important causesSome elements of the history suggestive of coronary disease are also important for other cases such as:* Pain brought on by exertion and relieved by rest is certainly indicative of angina, but psychogenicdisease and esophageal spasm may behave in similar fashion. A check for anxiety, depression, panicdisorder and life long history of other bodily complaints may suggest a psychogenic origin. Heart bum,dysphagia and an absence of CHD risk factors raise the possibility of esophageal disease.* Episodes that last hours to days provide further evidence of a non-cardiac origin.* Prompt response to GTN is another characteristic feature of CHD, but esophageal spasm, coronarymicrovascular disease, cystic duct spasm and even some psychogenic etiologies may also respond tonitrates.* Chest pain brought on by eating may be due to angina, but in the absence of other risk factors forCHD, one needs to consider gastro-esophageal or pancreatobiliaiy pathology.* Pain worsened by deep inspiration or cough is a hallmark of pleural irritation, but it is also suggestiveof pericarditis and chest wall pathology.* Focal chest wall tenderness narrows the differential diagnosis to a chest wall origin.* Pneumothorax should come to mind when pleuritic pain is sudden in onset and accompanied bydyspnea in a young patient with a previous H/O pneumothorax or long standing bullous emphysema.* Pleuritic pain in the setting of an episode of minor viral respiratory disease suggests pleurodynia.* Sudden onset of maximally severe pain is a worrisome presentation, necessitating consideration ofaortic dissection. If the episode is accompanied by a new neurologic deficit or a syncopal episode, thenurgent hospitalization is indicated.Physical ExaminationThere is no standard physical examination for the patient with chest pain. The appropriate examinationis based on the hypotheses suggested by the history. General appearance and vital signs can be telling.* Anxious, sighing, hyperventilating individual who complaints of constant chest tightness is likely tobe suffering from an anxiety disorder.* Tachypnea and tachycardia with pleuntie pain are indicative of pulmonary embolism.* Blood pressure difference between extremities for aortic dissection.* Skin for cyanosis, herpetic rash, pallor etc.* ther examination which will be helpful are:* Fundi for atherosclerotic, diabetic or hypertensive disease.* Slow rising carotid pulse in aortic stenosis* JVP transiently elevated during an ischemic episode.* On examinatiOn of the heart look for (1) forceful or having left ventricular impulse which isindicative of significant aortic stenosis (AS) or a hypertrophic cardiomyopathy; (2) Signs of ischemicmyocardial dysfunction, such as loss of physiologic splitting of the 2nd heart sound and developmentof 4th heart sound; (3) systolic ejection murmur of AS* If the chest pain is pleuritic, rub may be present.In abdomen look for any tenderness in the epigatric and right upper quandrant region for cholecystitis.* Ailperipheral pulses are checked for any evidence of aortic dissection.* Neruological examination for new focal deficit or aortic dissection.Laboratory studiesIt should always be based on the working differential suggested by the history and physicalexamination.1. Coronary heart disease (CHD)We can divide patients who have suspected coronary heart disease in 3 groups3.a) Clinically high risk: These are the ones with a classic angina history, CHD risk factors, a positivefamily history, a few crackles, a fourth heart sound and loss of physiologic splitting they have such ahigh probability of CHD that diagnostic testing will add little except cost. One can proceed directly tomanagement.b) Clinically low risk: Patients with clearly non-anginal chest pain, no CHD risk factors or familyhistory and a normal cardiac examination have such a low probability of CHD that testing, is likely togenerate only negative or false - positive results and excessive medical bills. In this category, even aCHD test with high sensitivity and specificity like Thallium stress testing will perfonnpoorly.Occasionally, arresting ECG is obtained to reassure the patient and family.c) Clinically Intermediate Risk: These are the ones who present with atypical chest pain, a singlecardiac risk factor, questionable fourth heart sound. In such persons, a positive or negative test result islikely to have a significant effect on the post test probability of CHD and careful design of anevaluation program is indicated.II. Suspected Esophageal DiseaseUsually clinical presentation rules out coronary heart disease and the patient responds symptomaticallyto measures that reduce reflux and spasm.Chest pain due to adisorderof esophageal motility is not easy to document. A trial of antacids or H2blocker therapy is a helpful empirical measure.III. Pleuritic chest paina) Suspected pulmonary embolization: Patients should have a chest radiograph In short, history,physical examination and x-ray can be used to identify patients who might have an embolism andrequire further assessment. b) Suspected infection: In such cases chest radiograph may also revealpnemonitis.Pneumococcal pneumonia and tuberculosis often present with acute pleuritic pain and may be mistakenclinically for pulmonary embolus.c) Suspected pneumothorax: Suspicion of pneumothorax is an indication fora chest film.IV. PsychogenicThe anxious patient with psychogenic pain may find a chest X-ray and/or ECG reassuring. Repeatingtest “just to be sure” may begin to undermine the patient’s confidence in the physician’s explanationand even heighten anxiety.It is important to realize that as many as 10 percent of cases remain undiagnosed, even after careful andthorough evaluation.a) Symptomatic relief: Relief of pain must be based on an etiologic diagnosis. To simply suppress thepain with analgesics or sedatives before a diagnosis is made may hide important clues.However, musculoskeletal forms of chest pain may require analgesia. An antacid regimeno r H2blockers are helpful in patients with esophagitis. Nitrates and Ca- channel blocker are of benefit topatients with esophageal spasm. Patients with depression or panel disorder require specific therapydirected at the underlying psychopathology.b) Patient Education: A careful and thorough explanation is essential to avoid precipitating a cardiacneurosis or unnecessary visits to several physicians forevaluationof chest pain Patients making manyvisit usually harbor unexplored concerns that have not been adequately addressed.c) Indications for referral: Urgent referral to the nearest emergency room is indicated for the patientwith severe anginal chest pain lasting over 30 minutes.Similarly, the patient with suspected pulmonary embolization, pneumothorax or aortic dissectionrequires immediate hospitalization.The patient with panic disorder or depression severe enough to cause disabling symptoms deservesconsideration for psychiatric referral.Acknowledgement I am grateful to Mr. Jahangir Alaru for the secretarial support.References 1. Birdwell BG, Herbers JE, Kroenke K. Evaluating chest pain: The patient’s presentationstyle altersthephysician’sdiagnostic approach. Arch. Intern. Med., 1993;153: 153.582. Cannon RO. Chest pain with normal coronary angiograms. N. Engi J. Med 1993;328: 1706.7.3. Sox HC, Kickam DH, Lee TM et al. Using the patient’s history to estimate the probability ofcoronary artery diseases: A comparison of primary care and referral practices. Am. J. Med., 1990;89:7-9.

Evaluation of chest pain in general practice

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