GBS is a post-infectious poly-neuropathy involving mainly motor but sometimes also sensory and autonomic nerves. This is an epidemiological report on seasonal & monthly distribution of GBS & differences in GBS incidence between male & female in Punjab, Pakistan. Objective: To determine the seasonal variation, age and gender differentiation in children with GBS along with EMG/NCS findings. Study Design: Retrospective, observational,cross sectional study. Place and duration of study: Department of Neurology, Childrens Hospital & The Institute of Child Health, Lahore from January 2014 to December 2014. METHODS: We extracted data from multi centers retrospectively in a 1 year period (January 2014- December 2014). In order to compare the frequency of GBS in different months & seasons we used the chi-square test. RESULTS: There was male predominance with 52.11% (n=37). Highest number of cases (70.4%) were found in age group (11-18 Years) (n=50). Seasonal (P=0.01) and monthly (P=0.02) variation among GBS was observed throughout the year with more prevalence in summer (49.29%) followed by spring (25.35%). Regional date of Punjab revealed highest number of cases 36.6% (n=26) in South Punjab followed by west Punjab 28.16% (n=20) CONCLUSION: Our study shows that there is significant monthly and seasonal variation in the admission rate of patients with GBS in Punjab