In this paper the performance of a genetically selected radial basis functions
neural network is evaluated for non-invasive two-point temperature estimation in a homogeneous medium, irradiated by therapeutic ultrasound at physiotherapeutic
levels. In this work a single neural network was assigned to estimate the temperature
profile at the two considered points, and more consistent results were obtained than
when considering one model for each point. This result was possible by increasing the
model complexity. The best model predicts the temperature from two unseen data sequences during approximately 2 hours, with a maximum absolute error less than 0.5 oC, as desired for a therapeutic temperature estimator
