Antinori, A.

Bruun, T.

Collins, S.

Daskalopoulou, M.

Gilson, R.

Group, Cognitive Impairment in People with HIV in the European Region (CIPHER) Study

Haddow, L.

Lampe, F.

Laverick, R.

Rodger, A.

Speakman, A.

Vassilenko, A.

English

We determined factors associated with self-reported decline in activities of daily living (ADLs) and symptoms of cognitive impairment in HIV positive adults in 5 European clinics.HIV+ adults underwent computerized and pen-and-paper neuropsychological tests and questionnaires of cognitive symptoms and ADLs. We considered cognitive function in 5 domains, psychosocial factors, and clinical parameters as potentially associated with symptoms. Separate regression analyses were used to determine factors associated with a decline in ADL (defined as self-reported decline affecting ≥2 ADLs and attributed to cognitive difficulties) and self-reported frequency of symptoms of cognitive impairment. We also estimated the diagnostic accuracy of both questionnaires as tests for cognitive impairment.Four hundred forty-eight patients completed the assessments [mean age 45.8 years, 84% male, 87% white, median CD4 count 550 cells/mm, median time since HIV diagnosis 9.9 years, 81% virologically suppressed (HIV-1 plasma RN

Edinburgh Research Explorer

Self-Reported Decline in Everyday Function, Cognitive Symptoms, and Cognitive Function in People With HIV.

https://www.pure.ed.ac.uk/ws/files/132224214/Self_Reported_Decline_in_Everyday_Function_.16.pdf

Self-Reported Decline in Everyday Function, Cognitive Symptoms, and Cognitive Function in People With HIV.

Abstract

Similar works

Full text

Available Versions

Edinburgh Research Explorer