Guido, Stefano

Innes, Elisabeth A.

Katzer, Frank

Milne, Elspeth

Nanjiani, Ian

Trends in Parasitology

English

The protozoan Neospora caninum is a primary infectious cause of abortion in cattle that causes significant economic losses worldwide. As effective vaccines and licensed pharmacological treatments are currently unavailable, control measures rely on biosecurity and management practice. Serological diagnosis plays a crucial role in the identification of infected animals and a number of tests have been developed. However, due to the particular dynamics of the host-parasite interaction and to the characteristics of the currently used diagnostic tools, a proportion of infected cattle may not be reliably identified and can potentially undermine efforts towards the control of bovine neosporosis. Here, current diagnostic methods for N. caninum infection in cattle and the advancements required to support effective control strategies are discussed

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     Edinburgh Research Explorer                                      Serology-based diagnostics for the control of bovineneosporosisCitation for published version:Guido, S, Katzer, F, Nanjiani, I, Milne, E & Innes, EA 2015, 'Serology-based diagnostics for the control ofbovine neosporosis', Trends in Parasitology. https://doi.org/10.1016/j.pt.2015.11.014Digital Object Identifier (DOI):10.1016/j.pt.2015.11.014Link:Link to publication record in Edinburgh Research ExplorerDocument Version:Peer reviewed versionPublished In:Trends in ParasitologyGeneral rightsCopyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s)and / or other copyright owners and it is a condition of accessing these publications that users recognise andabide by the legal requirements associated with these rights.Take down policyThe University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorercontent complies with UK legislation. If you believe that the public display of this file breaches copyright pleasecontact openaccess@ed.ac.uk providing details, and we will remove access to the work immediately andinvestigate your claim.Download date: 11. May. 2020Abortion Bradyzoites within tissue cysts Exogenous  transmission Endogenous transmission Oocysts A Primary infection Persistently infected calf Breeding of persistently infected heifer Vertical route RECRUDESCENCE OF INFECTION Definitive  host Horizontal route Intermediate host Tachyzoites ACUTE INFECTION PERSISTENT  INFECTION B C D E F 

Serology-based diagnostics for the control of bovine neosporosis

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