A RP-HPLC method has been developed and validated for the estimation of telmisartan in bulk and pharmaceutical dosage form. A RP-HPLC isocratic separation was achieved on C18 column (250.6 mm i.d., 5m) utilizing a mobile phase comprising of methanol and acetonitrile in the ratio of 90: 10(v/v) and the eluents from the column were detected using a variable wavelength detector at 237nm. The proposed method has permitted the quantification of telmisartan in the linearity range of 20-100g/ml and the flow rate was maintained at 1ml/min. The column was maintained at ambient temperature and the complete separation was achieved for telmisartan in an overall analytical run time of approximately 10 minutes. The retention time of telmisartan was found to be 3.3 minutes. The limit of detection and limit of quantification were found to be 2.82 and 8.54 ?g/ml, respectively. The percentage recovery was found to be in between 87.3 to 103.18%. The method was found to be suitable for the routine quality control analysis of telmisartan in bulk drug and formulation. The method was validated as per ICH guidelines
