Antibiogram of nasal methicillin resistant Staphylococcus aureus (MRSA) from antenatal clinic attendees in a tertiary hospital, South-South Nigeria

Abstract

The antibiogram of nasal methicillin resistant Staphylococcus aureus (MRSA) from pregnant women attending University of Uyo Teaching Hospital was investigated using standard microbiological procedures. Out of 772 women, 180(23.3%) harboured nasal MRSA while 592 (76.7%) had MSSA (Methicillin Sensitive Staphylococcus aureus). The highest frequency (33.3%) occured at week 16 while the lowest occured at week 36 of the pregnancy period. Evaluation by logistic regression showed no risk factor involvement for MRSA. The patients were evaluated on their first visit (booking) therefore the MRSA were likely community-acquired. Antibiogram of isolates showed sensitivity mostly to clindamycin (80%), amoxacillin-clavulanic acid (76.7%), ceftriazone (69.4%) and resistance to co-trimoxazole (51.7%). The asymptomatic nasal colonisation of MRSA in pregnant women may therefore be a risk factor for serious systemic infection after delivery

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