The combination of microfluidic with Synchrotron Radiation Circular Dichroism (SRCD) is highly promising for the study of protein interactions and misfolding in real time. However, due to the strong absorption of many materials in the far-UV region, the fabrication of microfluidic devices has been limited to fused silica devices. Here we present two device architectures, fabricated using conventional PDMS-based soft-lithography, compatible with SRCD
