This report documents the development and construction of a generic economic model for the healthcare services involved in prostate cancer treatment. It also presents findings of descriptive analyses on the disease burden and three cost-effectiveness analyses. Specifically, the objectives of this project were to: 1. Build a generic economic model structure; 2. Populate the model with data estimates; 3. Validate the generic model internally and externally; 4. Undertake descriptive analyses of costs and patient outcomes; and 5. Undertake three cost-effectiveness analyses comparing strategies of interest with the status quo and integrating the generic model structure