Ksheerbala Tail having Shaman rasayana and Brimhana properties. The content of the tail adds to its effect. Ksheerbala tail having contents of Bala (Sida cordifolia), Goksheer (Cow’s milk), and Sesame oil (Sesamum indicum), it normalizes the Vata and Pitta in the body and shows anti-inflammatory action. It is also given in almost all Authentic books Charak Samhita, Ashtang Hridya and Sushrut, with different names. It acts as a nervine tonic and strengthens the muscles and to provide better options to Non-Steroidal Anti-inflammatory Drugs (NSAIDs). Non-steroidal anti- inflammatory drugs owing to its exceedingly speckled side effects and adversities are in the verge of a moribund reliance. Ksheerbala Tail, a sage old Ayurved remedy remarkably emphasised in the treatment of Vata Vyadhi and Vatarakta is well used since ages as an anti-inflammatory medicine. Developing researches have demonstrated its efficacy to counter neuro toxicity and subsequently validated its neuro protective effect. Though, the much acclaimed traditional wisdom regarding its anti inflammatory action is neither scientifically appraised nor compared with any standards. It is also used for Abhyang in detoxication process. Vata Vyadhi is best treated by Basti chikitsa, Abhyang etc. Matra basti is a type of Sneha basti which provides nutrition as well as pacify the morbid Vata dosha. In this article mode of action of Ksheerbala Tail and its different routes of administration are compiled