Amongst invertebrates, molluscs show great variability in their nervous system ranging from primitive
arrangement in Chitons to the complex mass of fused ganglia forming the ‘brain’ of cephalopods. Most
of the effector organs used for pharmacological or physiological experiments. The neurosecretory cells
(NSCs) with their combination of neuronal and glandular capabilities are perfectly suited to translate a
neuronal input into the hormonal output best suited to long-term process. In this capacity, the NSCs
may produce hormones, which act directly upon the peripheral target or it may exert its effect indirectly
by influencing the activity of other non-neural, endocrine organs. Neurosecretory cells have been
detected in the cerebral, pedal and visceral ganglia of Lamellidens corrianus. The distribution and
biology of freshwater bivalve like Lamellidens corrianus is influenced by local ecological factors (like
temperature, pH, inorganic salts, type of soil etc.), water flow system and presence of micro-organisms,
teleost fishes and seasonal variations in these parameters. Nitrogenous excretory changes which include
ammonia in these molluscs is also influenced by these local ecological factors in which temperature is
plays very crucial role. It is well known fact that the high stress conditions during drought or severe
winter conditions have been conquered by several lineage of gastropods and sand bivalves and their
ability to enter the resistant or dormant stages (low food) protein catabolism increased. Present
investigation deals with the oxygen consumption and ammonia excretion ratio of these freshwater
pelecypode Lamellidens corrianus. Study on Lemellidens corrianus directed in understanding the
different behavioral and physiological aspects after cerebral ganglia removal and injection of their
extracts revealed significant changes during summer (April-May)
