Erechu, R.

Kakooza, S.

Kankya, C.

Litta-Mulondo, A.

Mbatidde, I.

Moodley, Arshnee

Ndoboli, D.

Roesler, U.

Tenhagen, Bernd-Alois

Waiswa, J.

Wieland, Barbara

Roesler, Uwe

CGSpace

BUILD-AMR: Mitigating agriculture-associated antimicrobial resistance in poultry value chains in UgandaB. Wieland1, A.Moodley1, I. Mbatidde1,2, D. Ndoboli1,2, B-A Tenhagen3, U.Roesler4, R. Erechu5, A. Litta-Mulondo6, S. Kakooza7, J. Waiswa7 and C. Kankya21International Livestock Research Institute; 2Makerere University; 3Federal Institute for Risk Assessment (Bfr); 4Freie Universität Berlin; 5National Animal Disease Diagnostic and Epidemiology Centre; 6National Livestock Resources Research Institute; 7VSF GermanyCross component collaborationBuild AMR and VPH• Sharing of laboratory protocols• Potential for additional collaborations since bacteriologic analyses will be conducted in the same labs at NaLIRRI and NADEC Major achievements• Capacity needs assessment completed by VSFG• Stakeholder mapping completed by VSFG• Development of PhD concept notesMajor challenges• COVID-19• Procurement difficulties• Delayed recruitmentProblem: Antimicrobial resistance is a global One Health challenge, top ten human health threat by WHO (2019), disproportionate burden in low- and middle-income countriesChallenge: Limited national data AMU and AMR in LMICs→ difficult to evaluate livestock associated AMR risks and identifying risk pathways contributing to AMR in humans in LMICs.→ no baseline data to measure success of AMR mitigating interventions. Approach:→ cross-sectional studies to identify AMR riskslongitudinal study to investigate temporal dynamics and transmission pathways→ risk assessment to evaluate risks→ identify interventions to reduce AMUGraphical representation of the AMR studies, outputs and outcomesThis document is licensed for use under the Creative Commons Attribution 4.0 International Licence. June 2020Activities completed since June 2019  • Recruitment of two PhD fellows and a Research Assistant• NaLiRRI’s new lab is functional with new equipment to boost capacity for analyses• VSFG recruited a staff for AMR componentOutputs since June 2019• Capacity needs assessment• Stakeholder mapping• PhD concept notesPhD Dickson Ndoboli PhD Irene Mbatidde Dreck AyebareS. KakoozaE.coli on a plate       Antibiotic suscep. testFunded byILRI thanks all donors and organizations which globally support its work through their contributions to the CGIAR Trust Fund.Risk assessment for AMR in peopleModes of transmission of AMR between sources →Transmission modelling Value of training/interventions as a risk mitigation measureStudy 1: Cross-sectiona study in 2 districts (n=360 farms):-AM use patterns -AMR prevalence in poultryStudy 2: Longitudinal-transmission study (40 farms-dif.system)-Patterns of AM use -Monitoring production data-Transmission pathway (molecular epidemiology)Training on AM use and other inteerventions to mitigate AMR risks-Monitor changes in KAP-Monitor changes in AMR and production parametersStudy 2: Cross-sectional study-Chicken meat and/or egges at retail-AMR and antibiotic residuesPolicy advice to mitigate AMR risks in poultry productionDevelop training materialsAMU and AMR capacity needs assessment, KAP in value chain actorsScan to find out more

Mitigating agriculture-associated antimicrobial resistance in poultry value chains in Uganda

https://cgspace.cgiar.org/bitstream/10568/108689/6/BUILD_AMR.pdf

Mitigating agriculture-associated antimicrobial resistance in poultry value chains in Uganda

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