PMCID: PMC3423396This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Andrea Daverio

Claudio Pedone

Daniele Tosi

Enrico Zardi

Filomena Scarpa

Flaminia Olearo

Giordano Dicuonzo

Giorgio Sesti

Giovanni Mottini

Hervé Hilaire Tegue Simo

Michele Arigliani

Nicola Napoli

Paolo Pozzilli

Rocky Strollo

PLoS ONE

English

PubMed

Napoli, N

Zardi, E

Strollo, R

Arigliani, M

Daverio, A

Olearo, F

Tosi, D

Dicuonzo, G

Scarpa, F

Pedone, C

Tegue Simo, HH

Mottini, G

Pozzilli, P

Queen Mary Research Online

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Increased Carotid Thickness in Subjects with Recently-Diagnosed Diabetes from Rural Cameroon

We have recently shown a high prevalence of diabetes and obesity in rural Cameroon, despite an improved lifestyle. Diabetes in rural Africa remains underdiagnosed and its role in increasing risk of atherosclerosis in these populations is unknown. We investigated the prevalence of carotid atherosclerosis and cardiovascular risk factors in a population of subjects with recently-diagnosed diabetes from rural Cameroon.<0.05), but distensibility was similar between the two groups. At least one plaque >0.9 mm was found in 4%, 45.9% and 20% of diabetic subjects at the common, bulb or internal carotid, respectively. Only 25% of patients had an HbA1c<7%, while over 41.6% presented with marked hyperglycemia (HbA1c>9%). The prevalence of diabetic subjects with abnormal levels of LDL-cholesterol, triglycerides, HDL-cholesterol or blood pressure was 45%, 16.6%, 15% and 65.7%, respectively.Carotid thickness is increased in subjects with diabetes from a rural area of Cameroon, despite the relatively recent diagnosis. These findings and the high rate of uncontrolled diabetes in this population support the increasing concern of diabetes and cardiovascular diseases in African countries and indicate the need for multifaceted health interventions in urban and rural settings

Napoli Nicola

Zardi Enrico

Strollo Rocky

Arigliani Michele

Daverio Andrea

Olearo Flaminia

Tosi Daniele

Dicuonzo Giordano

Scarpa Filomena

Pedone Claudio

Tegue Simo Hervé Hilaire

Mottini Giovanni

Pozzilli Paolo

Public Library of Science (PLOS)

Napoli, N.

Zardi, E.

Olearo, F.

Tosi, D.

Dicuonzo, G.

Scarpa, F.

Pedone, C.

Tegue Simo, H. H.

Mottini, G.

Pozzilli, P.

ARIGLIANI, Michele

Archivio istituzionale della ricerca - Università degli Studi di Udine

Increased carotid thickness in subjects with recently-diagnosed diabetes from rural cameroon

BackgroundWe have recently shown a high prevalence of diabetes and obesity in rural Cameroon, despite an improved lifestyle. Diabetes in rural Africa remains underdiagnosed and its role in increasing risk of atherosclerosis in these populations is unknown. We investigated the prevalence of carotid atherosclerosis and cardiovascular risk factors in a population of subjects with recently-diagnosed diabetes from rural Cameroon.Methodology/principal findingsIn a case-control study, carotid intima-media thickness (IMT) was measured in 74 subjects with diabetes (diagnosed 0.9 mm was found in 4%, 45.9% and 20% of diabetic subjects at the common, bulb or internal carotid, respectively. Only 25% of patients had an HbA1c9%). The prevalence of diabetic subjects with abnormal levels of LDL-cholesterol, triglycerides, HDL-cholesterol or blood pressure was 45%, 16.6%, 15% and 65.7%, respectively.ConclusionsCarotid thickness is increased in subjects with diabetes from a rural area of Cameroon, despite the relatively recent diagnosis. These findings and the high rate of uncontrolled diabetes in this population support the increasing concern of diabetes and cardiovascular diseases in African countries and indicate the need for multifaceted health interventions in urban and rural settings

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Increased carotid thickness in subjects with recently-diagnosed diabetes from rural Cameroon.

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http://dx.doi.org/10.1371/journal.pone.0041316

Increased Carotid Thickness in Subjects with Recently-Diagnosed Diabetes from Rural Cameroon

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Queen Mary Research Online

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Archivio istituzionale della ricerca - Università degli Studi di Udine

Directory of Open Access Journals

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