This work was partly supported by funding from the Asthma UK Centre for Applied Research

A Sheikh

A Taylor

AH Anis

AJ Apter

AM Butz

British Thoracic Society/Scottish Intercollegiate Guidelines Network

C Griffiths

D Crocker

DR Morales

E Davidson

E Duran-Tauleria

ED Boudreaux

G Flores

G Netuveli

HS Nelson

HS Silver

J Paris

JE Miller

JJ Stephenson

JM Brotanek

KA Stewart

M Butz

M Patel

M Schatz

M Weatherall

ME Bollinger

MS Gilthorpe

N Ortega

RH Stanford

T Bryant-Stephens

T Diaz

T Mabotuwana

npj Primary Care Respiratory Medicine

PubMed

Hull, S

Homer, K

McKibben, S

Taylor, S

Pike, K

Griffiths, C

Queen Mary Research Online

European Respiratory Journal

Asthma prescribing practices, ethnicity and risk of hospital admission: An analysis of linked primary and secondary care records in East London

Sally Hull

Kate Homer

Shauna McKibben

Stephanie Taylor

Katy Pike

Chris Griffiths

Crossref

Inappropriate prescribing in primary care was implicated in nearly half of asthma deaths reviewed in the UK's recent National Review of Asthma Deaths. Using anonymised EMIS-Web data for 139 ethnically diverse general practices (total population 942,511) extracted from the North and East London Commissioning Support Unit, which holds hospital Secondary Uses Services (SUS)-linked data, we examined the prevalence of over-prescribing of short-acting β2-agonist inhalers (SABA), under-prescribing of inhaled corticosteroid (ICS) inhalers and solo prescribing of long-acting β2-agonists (LABA) to assess the risk of hospitalisation for people with asthma for 1 year ending August 2015. In a total asthma population of 35,864, multivariate analyses in adults showed that the risk of admission increased with greater prescription of SABA inhalers above a baseline of 1-3 (4-12 SABA: odds ratio (OR) 1.71; 95% confidence interval (CI) 1.20-2.46, ⩾13 SABA: OR 3.22; 95% CI 2.04-5.07) with increasing British Thoracic Society step (Step 3: OR 2.90; 95% CI 1.79-4.69, Step 4/5: OR 9.42; 95% CI 5.27-16.84), and among Black (OR 2.30; 95% CI 1.64-3.23) and south Asian adult populations (OR 1.83; 95% CI 1.36-2.47). Results in children were similar, but risk of hospitalisation was not related to ethnic group. There is a progressive risk of hospital admission associated with the prescription of more than three SABA inhalers a year. Adults (but not children) from Black and South Asian groups are at an increased risk of admission. Further work is needed to target care for these at-risk groups

Hull, SA

Taylor, SJ

UCL Discovery

Asthma prescribing, ethnicity and risk of hospital admission: an analysis of 35,864 linked primary and secondary care records in East London

Taylor, SJC

AbstractInappropriate prescribing in primary care was implicated in nearly half of asthma deaths reviewed in the UK’s recent National Review of Asthma Deaths. Using anonymised EMIS-Web data for 139 ethnically diverse general practices (total population 942,511) extracted from the North and East London Commissioning Support Unit, which holds hospital Secondary Uses Services (SUS)–linked data, we examined the prevalence of over-prescribing of short-acting β2-agonist inhalers (SABA), under-prescribing of inhaled corticosteroid (ICS) inhalers and solo prescribing of long-acting β2-agonists (LABA) to assess the risk of hospitalisation for people with asthma for 1 year ending August 2015. In a total asthma population of 35,864, multivariate analyses in adults showed that the risk of admission increased with greater prescription of SABA inhalers above a baseline of 1–3 (4–12 SABA: odds ratio (OR) 1.71; 95% confidence interval (CI) 1.20–2.46, ⩾13 SABA: OR 3.22; 95% CI 2.04–5.07) with increasing British Thoracic Society step (Step 3: OR 2.90; 95% CI 1.79–4.69, Step 4/5: OR 9.42; 95% CI 5.27–16.84), and among Black (OR 2.30; 95% CI 1.64–3.23) and south Asian adult populations (OR 1.83; 95% CI 1.36–2.47). Results in children were similar, but risk of hospitalisation was not related to ethnic group. There is a progressive risk of hospital admission associated with the prescription of more than three SABA inhalers a year. Adults (but not children) from Black and South Asian groups are at an increased risk of admission. Further work is needed to target care for these at-risk groups.</jats:p

Sally A Hull

Stephanie JC Taylor

http://discovery.ucl.ac.uk/1508434/1/pike_npjpcrm201649.pdf

Asthma prescribing, ethnicity and risk of hospital admission: an analysis of 35,864 linked primary and secondary care records in East London

Abstract

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Queen Mary Research Online

Crossref

UCL Discovery

Queen Mary Research Online

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