Ball, D

Joshi, N

Marks, I

Rampton, D

Journal of Crohn s and Colitis

English

Queen Mary Research Online

C.difficile infection rate in patients with IBD is falling in line with that of thegeneral populationMarks, I; Joshi, N; Ball, D; Rampton, D       For additional information about this publication click this link.http://qmro.qmul.ac.uk/jspui/handle/123456789/8862   Information about this research object was correct at the time of download; we occasionallymake corrections to records, please therefore check the published record when citing. Formore information contact scholarlycommunications@qmul.ac.uk2014-11-25 12:40:0710th Congress of ECCOTopic: Microbiology Type: Oral or digital oral presentation or hard copy poster Abstract no.: A-1379 Status: submitted Label attributes equipment I do NOT want my work to be considered for the nurses programme. Y-ECCO Basic Science Workshop No, I am NOT interested in presenting my work during the Y-ECCO Basic Science Workshop. Y-ECCO Abstract Awards Yes, this abstract qualifies to participate in the Y-ECCO Abstract Award process. IIS Abstract Award No, this abstract does NOT qualify to participate in the IIS Abstract Award process. C.difficile infection rate in patients with IBD is falling in line with that of the general populationI. Marks1, N. Joshi*1, D. Ball2, D. Rampton11Queen Mary, University of London, Blizard Institute, Centre for Digestive Diseases, London, United Kingdom, 2Barts Health NHS Trust, Medical Microbiology, London, United KingdomBackgroundSeveral studies have reported that the incidence of C.difficile infection (CDI) in patients with inflammatory bowel disease (IBD) continues to rise [1,2]. In the UK, the incidence of CDI in the general population has been falling since 2007. Our clinical suspicion that CDI was becoming less common in patients with IBD led us to investigate CDI rates in IBD patients between 2008 and 2013 to see if CDI in IBD is also in decline.MethodsResults of stool microbiology from all diarrhoeal samples submitted for C. difficile detection (as an ELISA for toxin B) over a 6-year period ending 2013 were assessed using the microbiology database at Barts Health NHS Trust, London. Electronic patient records for CDI-positive patients were analysed for a diagnosis of IBD at the time of infection.Results1079/25092 (4.3%) of all samples sent were positive for CDI, of which 49 (4.5%) were from patients with IBD. The median age (range) of the IBD CDI patients was 31.6 (1-88) years, and of the non-IBD patients 67.9 (1-98) years (p<0.0001). Of the IBD patients, 34 patients had ulcerative colitis, and 15 Crohn's disease (10 colonic, 3 ileocolonic, 2 ileal). The CDI rates in the entire group studied and in the non-IBD patients (as % of stools each year sent for investigation of CDI) decreased annually over the study period from about 7% in 2008 to 1.5% in 2013 (figure). The CDI rates in IBD patients were low throughout this period (<0.4% of stools sent). ConclusionsOverall CDI rates at our hospital are falling. A very low and constant proportion of patients with IBD test positive for CDI. Although it remains important to test for CDI in diarrhoeal patients with IBD, the incidence of this infection in IBD has now stabilised and has remained low since 2008.AuthorsFirst author: I. Marks Presented by: N. Joshi Submitted by: N. Joshi Conflict of interests: no "C.difficile infection rates 2008-2013"

I. Marks Presented by: N. Joshi Submitted by: N. Joshi Conflict of interests: no &quot;C.difficile infection rates 2008-2013&quot;

C.difficile infection rate in patients with IBD is falling in line with that of the general population

https://qmro.qmul.ac.uk/xmlui/bitstream/handle/123456789/8862/A-1379.pdf?sequence=5

C.difficile infection rate in patients with IBD is falling in line with that of the general population

Abstract

Similar works

Full text

Available Versions

Queen Mary Research Online