Fecha del documento: 1635-07-06. 3 páginasConsulta del Consejo de Estado a Felipe IV sobre el memorial remitido por el licenciado Dionisio Odonel, sacerdote irlandés, que vino a España huyendo de la herejía para aprender en las escuelas católicas y luego regresar a su patria a administrar los santos sacramentos. Solicita la limosna acostumbrada para los que van a la Misión de Irlanda para mudarse de traje y llevar los sagrados ornamentos sacerdotales.
El Consejo propone darle la limosna habitual.
Respuesta del rey: "Como parece".Proyecto Proyección Política y Social de la Comunidad Irlandesa en la Monarquía hispánica y en la América Colonial de la Edad Moderna(siglos XVI-XVIII) (HAR2009-11339 - subprograma HIST) del Ministerio de Economía y Competitividad en colaboración con el Consejo Superior de Investigaciones Científicas (CSIC), Embajada de Irlanda en Madrid, National University of Ireland (NUI) Maynooth, University College Dublin y Trinity College DublinConsejo de EstadoFelipe IVSí100 ducadosSí100 ducadosN

Aileen Clarke (470453)

Bee Tan (4279435)

Chris Stinton (3822172)

Colin Brown (832030)

Esther Robinson (736618)

Farah Seedat (644974)

Hannah Fraser (3822169)

Jacoby Patterson (4279432)

Julia Geppert (3822166)

Karoline Freeman (493517)

Noel McCarthy (3569720)

Olalekan Uthman (573234)

Samantha Johnson (493518)

Sian Taylor-Phillips (3533141)

BMC Pregnancy and Childbirth

Grupo de investigación Misión de Irlanda

Digital.CSIC

Concesión de viático al licenciado Dionisio Odonel, sacerdote irlandés, para ir a la Misión de Irlanda

BACKGROUND



Adverse events from intrapartum antibiotic prophylaxis (IAP) are poorly documented yet essential to inform clinical practice for neonatal group B Streptococcus (GBS) disease prevention. In this systematic review, we appraised and synthesised the evidence on the adverse events of IAP in the mother and/or her child.



METHODS



We searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane, and Science Citation Index from date of inception until October 16th 2016. Reference lists of included studies and relevant systematic reviews were hand-searched. We included primary studies in English that reported any adverse events from intrapartum antibiotics for any prophylactic purpose compared to controls. The search was not restricted to prophylaxis for GBS but excluded women with symptoms of infection or undergoing caesarean section. Two reviewers assessed the methodological quality of studies, using the Cochrane Risk of Bias tool, and the Risk of Bias Assessment Tool for Nonrandomised Studies. Results were synthesised narratively and displayed in text and tables.



RESULTS



From 2364 unique records, 30 studies were included. Despite a wide range of adverse events reported in 17 observational studies and 13 randomised controlled trials (RCTs), the evidence was inconsistent and at high risk of bias. Only one RCT investigated the long-term effects of IAP reporting potentially serious outcomes such as cerebral palsy; however, it had limited applicability and unclear biological plausibility. Seven observational studies showed that IAP for maternal GBS colonisation alters the infant microbiome. However, study populations were not followed through to clinical outcomes, therefore clinical significance is unknown. There was also observational evidence for increased antimicrobial resistance, however studies were at high or unclear risk of bias.



CONCLUSIONS



The evidence base to determine the frequency of adverse events from intrapartum antibiotic prophylaxis for neonatal GBS disease prevention is limited. As RCTs may not be possible, large, better quality, and longitudinal observational studies across countries with widespread IAP could fill this gap.



TRIAL REGISTRATION



CRD42016037195 

Seedat, Farah

Stinton, Chris

Patterson, Jacoby

Geppert, Julia

Tan, Bee K

Robinson, Esther R

McCarthy, Noel Denis

Uthman, Olalekan A

Freeman, Karoline

Johnson, Samantha Ann

Fraser, Hannah

Brown, Colin Stewart

Clarke, Aileen

Taylor-Phillips, Sian

Heart of England: HEFT Repository

Adverse events in women and children who have received intrapartum antibiotic prophylaxis treatment: a systematic review.

BACKGROUND: Adverse events from intrapartum antibiotic prophylaxis (IAP) are poorly documented yet essential to inform clinical practice for neonatal group B Streptococcus (GBS) disease prevention. In this systematic review, we appraised and synthesised the evidence on the adverse events of IAP in the mother and/or her child. METHODS: We searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane, and Science Citation Index from date of inception until October 16th 2016. Reference lists of included studies and relevant systematic reviews were hand-searched. We included primary studies in English that reported any adverse events from intrapartum antibiotics for any prophylactic purpose compared to controls. The search was not restricted to prophylaxis for GBS but excluded women with symptoms of infection or undergoing caesarean section. Two reviewers assessed the methodological quality of studies, using the Cochrane Risk of Bias tool, and the Risk of Bias Assessment Tool for Nonrandomised Studies. Results were synthesised narratively and displayed in text and tables. RESULTS: From 2364 unique records, 30 studies were included. Despite a wide range of adverse events reported in 17 observational studies and 13 randomised controlled trials (RCTs), the evidence was inconsistent and at high risk of bias. Only one RCT investigated the long-term effects of IAP reporting potentially serious outcomes such as cerebral palsy; however, it had limited applicability and unclear biological plausibility. Seven observational studies showed that IAP for maternal GBS colonisation alters the infant microbiome. However, study populations were not followed through to clinical outcomes, therefore clinical significance is unknown. There was also observational evidence for increased antimicrobial resistance, however studies were at high or unclear risk of bias. CONCLUSIONS: The evidence base to determine the frequency of adverse events from intrapartum antibiotic prophylaxis for neonatal GBS disease prevention is limited. As RCTs may not be possible, large, better quality, and longitudinal observational studies across countries with widespread IAP could fill this gap. TRIAL REGISTRATION: CRD42016037195 

F Seedat (7718243)

C Stinton (7718249)

J Patterson (7718252)

J Geppert (7718255)

B Tan (7718261)

ER Robinson (7718273)

ND McCarthy (7718276)

OA Uthman (7718270)

K Freeman (7718258)

SA Johnson (7718264)

H Fraser (7718267)

CS Brown (7718246)

A Clarke (3285192)

S Taylor-Phillips (7718279)

Leicester Research Archive

Adverse events from intrapartum antibiotic prophylaxis (IAP) are poorly documented yet essential to inform clinical practice for neonatal group B Streptococcus (GBS) disease prevention. In this systematic review, we appraised and synthesised the evidence on the adverse events of IAP in the mother and/or her child.We searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane, and Science Citation Index from date of inception until October 16th 2016. Reference lists of included studies and relevant systematic reviews were hand-searched. We included primary studies in English that reported any adverse events from intrapartum antibiotics for any prophylactic purpose compared to controls. The search was not restricted to prophylaxis for GBS but excluded women with symptoms of infection or undergoing caesarean section. Two reviewers assessed the methodological quality of studies, using the Cochrane Risk of Bias tool, and the Risk of Bias Assessment Tool for Nonrandomised Studies. Results were synthesised narratively and displayed in text and tables.From 2364 unique records, 30 studies were included. Despite a wide range of adverse events reported in 17 observational studies and 13 randomised controlled trials (RCTs), the evidence was inconsistent and at high risk of bias. Only one RCT investigated the long-term effects of IAP reporting potentially serious outcomes such as cerebral palsy; however, it had limited applicability and unclear biological plausibility. Seven observational studies showed that IAP for maternal GBS colonisation alters the infant microbiome. However, study populations were not followed through to clinical outcomes, therefore clinical significance is unknown. There was also observational evidence for increased antimicrobial resistance, however studies were at high or unclear risk of bias.The evidence base to determine the frequency of adverse events from intrapartum antibiotic prophylaxis for neonatal GBS disease prevention is limited. As RCTs may not be possible, large, better quality, and longitudinal observational studies across countries with widespread IAP could fill this gap.CRD42016037195 

Patterson, Joseph P.

Tan, Bee K.

Robinson, Esther R.

McCarthy, Noel D.

Uthman, Olalekan A.

Warwick Research Archives Portal Repository

Adverse events in women and children who have received intrapartum antibiotic prophylaxis treatment : a systematic review.

The Additional file contains three items. The first shows the search strategy used for Medline that was adapted for other databases; the second lists the studies that were excluded (n = 227) at the full text stage with the reasons for their exclusion; and the third is Table S1. that summarises all of the included studies, their characteristics, and their findings. (DOCX 225Â kb

FigShare

Additional file 1: of Adverse events in women and children who have received intrapartum antibiotic prophylaxis treatment: a systematic review

Abstract Background Adverse events from intrapartum antibiotic prophylaxis (IAP) are poorly documented yet essential to inform clinical practice for neonatal group B Streptococcus (GBS) disease prevention. In this systematic review, we appraised and synthesised the evidence on the adverse events of IAP in the mother and/or her child. Methods We searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane, and Science Citation Index from date of inception until October 16th 2016. Reference lists of included studies and relevant systematic reviews were hand-searched. We included primary studies in English that reported any adverse events from intrapartum antibiotics for any prophylactic purpose compared to controls. The search was not restricted to prophylaxis for GBS but excluded women with symptoms of infection or undergoing caesarean section. Two reviewers assessed the methodological quality of studies, using the Cochrane Risk of Bias tool, and the Risk of Bias Assessment Tool for Nonrandomised Studies. Results were synthesised narratively and displayed in text and tables. Results From 2364 unique records, 30 studies were included. Despite a wide range of adverse events reported in 17 observational studies and 13 randomised controlled trials (RCTs), the evidence was inconsistent and at high risk of bias. Only one RCT investigated the long-term effects of IAP reporting potentially serious outcomes such as cerebral palsy; however, it had limited applicability and unclear biological plausibility. Seven observational studies showed that IAP for maternal GBS colonisation alters the infant microbiome. However, study populations were not followed through to clinical outcomes, therefore clinical significance is unknown. There was also observational evidence for increased antimicrobial resistance, however studies were at high or unclear risk of bias. Conclusions The evidence base to determine the frequency of adverse events from intrapartum antibiotic prophylaxis for neonatal GBS disease prevention is limited. As RCTs may not be possible, large, better quality, and longitudinal observational studies across countries with widespread IAP could fill this gap. Trial registration CRD42016037195 

Farah Seedat

Chris Stinton

Jacoby Patterson

Julia Geppert

Bee Tan

Esther R. Robinson

Noel Denis McCarthy

Olalekan A. Uthman

Karoline Freeman

Samantha Ann Johnson

Hannah Fraser

Colin Stewart Brown

Aileen Clarke

Sian Taylor-Phillips

Directory of Open Access Journals

Adverse events in women and children who have received intrapartum antibiotic prophylaxis treatment: a systematic review

Crossref

HEFT Repository

https://figshare.com/articles/Additional_file_1_of_Adverse_events_in_women_and_children_who_have_received_intrapartum_antibiotic_prophylaxis_treatment_a_systematic_review/5248549

Concesión de viático al licenciado Dionisio Odonel, sacerdote irlandés, para ir a la Misión de Irlanda

Abstract

Similar works

Full text

Available Versions