This research examines the neurological similarities between schizophrenia and major depressive disorder with psychotic features to compare the manifestations of psychosis in each disorder. Both disorders often involve symptoms of psychosis, although the disorders overall are very different. We hypothesize that the neurological similarities between schizophrenia and major depressive disorder with psychotic features will provide researchers with the strategies needed to develop a treatment for psychotic symptoms. In order to test this hypothesis, five related studies were gathered for each disorder, and three studies were gathered for psychosis. These studies were then analyzed to pinpoint any similarities among factors for psychosis, and this analysis allowed for the determination of whether the hypothesis would be rejected. The results indicated that many of the similarities between the two disorders cannot be verified because of the lack of substantial research
