A HS-SPME-GC/MS Method for the Determination of Suspected Allergens in Essential Oils, Flavour, Fragrances and Cosmetics

Abstract

An analytical methodology suitable to identify and quantify (as limit test) 24 compounds in vegetable materials (fluid and dry extracts) was developed according to EU Directive 2003/15/EC (suspected allergens). Static headspace solid-phase microextraction (HS-SPME) was directly perfomed. Automated mass spectral deconvolution and identification system (AMDIS) program was applied on GC-MS data through use of a library of mass spectra including RI-values