Sixty hundred and twenty-six case histories of patients with renal-cell carcinoma, who underwent nephrectomy at the Department of Oncourology, P.A. Herzen Moscow Research Oncological Institute, in November 1992 to November 2005, have been restrospectively analyzed.Results. Metastatic lymph nodal lesion was identified in 23 (6.49%) patients of 354 patients with renal-cell carcinoma without distant metastasis, who had undergone regional lymphadenectomy. Metastatic regional lymph nodal lesions were found in 9 (2.54%) patients on preoperative examination (as verified by ultrasound study and computed tomography). Metastatic lymph nodal lesion was intraoperatively suspected in 3 (0.85%) patients. This was revealed in 11 (3.11%) patients after planned histological study.Conclusion. The frequency of metastatic regional lymph nodal lesions is 3.11% in patients with early renal-cell carcinoma with unaltered regional lymph nodes, as shown by preoperative and operative examinations. In renal-cell carcinoma, the probability of metastasis into the regional lymph nodes increases in patients with a more 5-cm renal tumor, in those with non-clear or mixed carcinoma, and or those with a locally advanced tumorous process.
