Rotavirus infection occupies an important place in the
structure of infectious diseases and is the main reason of morbidity
and mortality in young children. According to WHO experts, almost
every child suffers from rotavirus gastroenteritis during the first five
years of life, regardless of social and economic status and place of
residence. Children under the age from 6 to 24 months suffer from
rotavirus infection the most often. According to WHO, the incidence
in different countries ranges from 250 to 3,000 per 100,000 children.
More than 111 million cases of rotavirus gastroenteritis are
diagnosed every year. The course of the disease mostly depends on
the immune system of the patient. A special place here belongs to the
cell role, namely the immunoregulatory index, which is the ratio of
CD4 + to CD8 + T-lymphocytes and is an indicator of body's defense
system against infections
